3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- Product Name
- 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- CAS No.
- 781652-57-1
- Chemical Name
- 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- Synonyms
- CDPPB;mGluR5 Ligand, CDPPB;3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide;mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem;Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-
- CBNumber
- CB32498277
- Molecular Formula
- C23H16N4O
- Formula Weight
- 364.4
- MOL File
- 781652-57-1.mol
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Property
- Melting point:
- 210-212°C
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥5mg/mL at warmed to 60°C
- form
- powder
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0235
- Product name
- CDPPB
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $113
- Updated
- 2024/03/01
- Product number
- 445865
- Product name
- mGluR5 Ligand, CDPPB
- Packaging
- 1mg
- Price
- $129
- Updated
- 2022/05/15
- Product number
- SML0235
- Product name
- CDPPB
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $579
- Updated
- 2024/03/01
- Product number
- 3235
- Product name
- CDPPB
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $195
- Updated
- 2021/12/16
- Product number
- 3235
- Product name
- CDPPB
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $818
- Updated
- 2021/12/16
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Chemical Properties,Usage,Production
Uses
CDPPB may be used in mGluR5-mediated cell signaling studies.
Uses
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
Biochem/physiol Actions
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
storage
+4°C
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Suppliers
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8449
- Advantage
- 60
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58